Staff Profile

Prof Maria Balda

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Personal Profile

Name: Maria Balda Email: m.balda@ucl.ac.uk
Title: Prof Tel: 20 7608 6861
Department: Inst Ophthalmology - Cell Biology Fax: 20 7608 4034
Position: Reader in Cell Biology Address: 11-43 Bath street, , London, London EC1
Research Domain: Basic Life Sciences, Cardiometabolic Science, Neuroscience Web Page: Personal Web Page

Profile

Research Description

Epithelial and endothelial cells form selective barriers between compartments of different composition. To perform this function, they have a specialised intercellular junctional complex (tight and adherens junctions, desmosomes and gap junctions). Assembly and disassembly of the junctional complex is tightly regulated during physiological conditions, but is disturbed in pathological situations such as wounds, inflammation, neovascularisation or transformation. Our research interest is to understand the molecular mechanisms through which tight junctions regulate paracellular permeability, cell proliferation and gene expression as well as to find out whether and how the tight junction signalling pathways interact with related signalling pathways triggered by cell-cell and cell-extracellular matrix interactions. Our findings will be used not only to understand physiologically complex processes ranging from tubulogenesis of epithelial and endothelial cells to the development of the eye but also to develop therapeutic tools to reverse pathological conditions such as tumorigenesis and proliferative or degenerative eye diseases.

Research Activities

Differentiation of polarised epithelia

Signal Transduction in Vascular Endothelial Cells

Education Description

2002-2003 Learning and Teaching in High Education Programme. Module I: Portfolio "Exploring Learning".Departement of Education and Professional Development. UCL.
2002-2004  Participation in the course on Molecular Basis of Disease Pathway. Module on Cell adhesion in health anddisease. Lecture on Tight junctions in health and disease.Department of Biology. Imperial College. London.UK
2004-2005 Learning and Teaching in HighEducation Programme. Module II: Portfolio "Towards the develop of thescientist mind". Department of Education and Professional Development.UCL. Certificate.
        2006  Participation in the course on Cytoskeleton and cell adhesion, LMCB, UCL
2009          Participation in the Master in Science course on Ocular Cell Biology, UCL Institute of Ophthalmology.




















UCL Collaborators

Prof John Greenwood; Dr Virginia Calder; Prof Philip Luthert; Dr Patric Turowski; Dr Marcus Fruttiger; Prof Robin Ali; Prof Karl Matter; Prof James Bainbridge

External Collaborators

Publications

    2012

    • Nie M, Balda MS, Matter K (2012). Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival.. Proc Natl Acad Sci U S A, 109(27), 10897 - 10902. doi:10.1073/pnas.1118822109
    • Terry SJ, Elbediwy A, Zihni C, Harris A, Bailly M, Charras G, Balda M, Matter K (2012). Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion. PLoS One, In press, - .
    • Elbediwy A, Zihni C, Terry SJ, Clark P, Matter K, Balda MS (2012). Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.. J Cell Biol, 198(4), 677 - 693. doi:10.1083/jcb.201202094

    2011

    • Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K (2011). Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.. Nat Cell Biol, 13(2), 159 - 166. doi:10.1038/ncb2156

    2010

    • Tsapara A, Luthert P, Greenwood J, Hill CS, Matter K, Balda MS (2010). The RhoA Activator GEF-H1/Lfc Is a TGF-β Target Gene and Effector that Regulates α-Smooth Muscle Actin Expression and Cell Migration. Molecular Biology of the Cell, , - . doi:10.1091/mbc.E09-07-0567
    • Steed E, Balda MS, Matter K (2010). Dynamics and functions of tight junctions. Trends in Cell Biology, , - . doi:10.1016/j.tcb.2009.12.002
    • McCrea P, Gu D, Balda MS (2010). Junctional music that the nucleus hears: Cell-cell junction signaling and the modulation of gene activity.. In Nelson J, Fuchs E (Ed.), Cell-cell Junctions. Cold Spring Harbor Perspectives in Biology (pp. 265 - 294). : .
    • Georgiadis A, Tschernutter M, Bainbridge JW, Balaggan KS, Smith AJ, Balda MS, Matter K, Ali RR (2010). Lentivirus-Mediated Silencing of Junctional Components in the Retinal Epithelium Causes EMT.
    • Lima WR, Parreira KS, Devuyst O, Caplanusi AN, Kuli F, Marien B, Smissen PV, Alves PM, Verroust P, Christensen EI, Terzi F, Matter K, Balda MS, Pierreux CE, Courtoy PJ (2010). ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells. Journal of the American Society of Nephrology, 21, 478 - 488. doi:10.1681/ASN.2009070698
    • Georgiadis A, Tschernutter M, Bainbridge JW, Balaggan KS, Mowat F, West EL, Munro PM, Thrasher AJ, Matter K, Balda MS, Ali RR (2010). The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.. PLoS One, 5(12), e15730 - . doi:10.1371/journal.pone.0015730
    • Terry S, Nie M, Matter K, Balda MS (2010). Rho signaling and tight junction functions. Physiology, 25, 16 - 26. doi:10.1152/physiol.00034.2009
    • Larre I, Lazaro A, Contreras RG, Balda MS, Matter K, Flores-Maldonado C, Ponce A, Flores-Benitez D, Rincon-Heredia R, Padilla-Benavides T, Castillo A, Shoshani L, Cereijido M (2010). Ouabain modulates epithelial cell tight junction.. Proc Natl Acad Sci U S A, 107(25), 11387 - 11392. doi:10.1073/pnas.1000500107

    2009

    • Matter K, Balda MS (2009). SIGNALLING AT TIGHT JUNCTIONS AND REGULATION OF GENE EXPRESSION IN EPITHELIAL CELLS.
    • Abouhamed M, Grobe K, San IV, Thelen S, Honnert U, Balda MS, Matter K, Bähler M (2009). Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus. Molecular Biology of the Cell, 20, 5074 - 5085. doi:10.1091/mbc.E09-04-0291
    • Steed E, Rodrigues NT, Balda MS, Matter K (2009). Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family. BMC Cell Biology, 10, 95 - .
    • Nie M, Aijaz A, Leefa Chong San IV, Balda MS, Matter K (2009). The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription. EMBO Report, 10, 1125 - 1131.
    • Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH (2009). Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin. Mol.Biol.Cell, 20(3), 1089 - 1101. doi:10.1091/mbc.E08-06-0566
    • Balda MS, Matter K (2009). Tight junctions and the regulation of gene expression. Biochim.Biophys.Acta, 1788(4), 761 - 767. doi:10.1016/j.bbamem.2008.11.024
    • Unkruer B, Pekcec A, Fuest C, Wehmeyer A, Balda MS, Horn A, Baumgartner W, Potschka H (2009). Cellular localization of Y-box binding protein 1 in brain tissue of rats, macaques, and humans. BMC Neuroscience, 10, - . doi:10.1186/1471-2202-10-28
    • Pekcec A, Unkruer B, Fuest C, Wehmeyer A, Balda MS, Horn A, Baumgartner W, Potschka H (2009). Cellular localization of Y-box binding protein 1 in brain tissue of rats, macaques, and humans.

    2008

    • Balda MS, Matter K (2008). Tight junctions at a glance. J.Cell Sci., 121(Pt 22), 3677 - 3682.

    2007

    • Pannequin J, Delaunay N, Darido C, Maurice T, Crespy P, Frohman MA, Balda MS, Matter K, Joubert D, Bourgaux JF, Bali JP, Hollande F (2007). Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure. Mol.Cancer Res., 5(11), 1147 - 1157.
    • Matter K, Balda MS (2007). Epithelial tight junctions, gene expression and nucleo-junctional interplay. J.Cell Sci., 120(Pt 9), 1505 - 1511.
    • Aijaz S, Sanchez-Heras E, Balda MS, Matter K (2007). Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2. BMC.Cell Biol., 8, 49 - .

    2006

    • Aijaz S, Balda MS, Matter K (2006). Tight junctions: molecular architecture and function. International Review of Cytology, 248, 261 - 298.
    • Sourisseau T, Georgiadis A, Tsapara A, Ali RR, Pestell R, Matter K, Balda MS (2006). Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1 regulated transcription factor ZONAB/DbpA. Molecular and Cellular Biology, 26(6), 2387 - 2398. doi:10.1128/MCB.26.6.2387-2398.2006
    • Kavanagh E, Buchert M, Tsapara A, Choquet A, Balda MS, Hollande F, Matter K (2006). Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin. Journal of cell science, 119(Pt 24), 5098 - 5105. doi:10.1242/jcs.03297
    • Tsapara A, Matter K, Balda MS (2006). The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB. Molecular Biology of the Cell, 17(3), 1322 - 1330. doi:10.1091/mbc.E05-06-0507
    • Kavangh E, Tsapara A, Matter K, Balda MS (2006). Tight junctions in the regulation of gene expression, cell proliferation and cell density. In Gonzalez-Mariscal L (Ed.), Selected Topics On Tight Junctions (pp. 101 - 116). : RG Landes Bioscience.

    2005

    • Shoshani L, Contreras RG, Roldan ML, Moreno J, Lazaro A, Balda MS, Matter K, Cereijido M (2005). The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells. Molecular Biology of the Cell, 16(3), 1071 - 1081. doi:10.1091/mbc.E04-03-0267
    • Matter K, Aijaz S, Tsapara A, Balda MS (2005). Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Current opinion in cell biology, 17(5), 453 - 458. doi:10.1016/j.ceb.2005.08.003
    • Balda MS, Georgiadis A, Tschernutter M, Balagan K, Ali RA, Vugler A, Greenwood J, Matter K (2005). ZONAB and ZO-1 are involved in the differentiation of retinal pigment epithelium.
    • Frankel P, Aronheim A, Kavanagh E, Balda MS, Matter K, Bunney TD, Marshall CJ (2005). RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity. The EMBO Journal, 24(1), 54 - 62. doi:10.1038/sj.emboj.7600497
    • Aijaz S, D'Atri F, Citi S, Balda MS, Matter K (2005). Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition. Developmental Cell, 8(5), 777 - 786. doi:10.1016/j.devcel.2005.03.003

    2004

    • Aijaz S, Goodrick S, Matter K, Balda MS (2004). Tight Junctions. In Ganden D, Ruckpaul K (Ed.), Encyclopaedic References of Genomes and Proteomics in Molecular Medicine (pp. - ). : Springer-Verlag International.
    • Braga VM, Balda MS (2004). Regulation of cell-cell adhesion.. Seminars in Cell and Developmental Biology, 15(6), 631 - 632.
    • Longshaw VM, Chapple JP, Balda MS, Cheetham ME, Blatch GL (2004). Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases.. Journal of Cell Science, 117(5), 701 - 710. doi:10.1242/10.1242/jcs.00905
    • Shoshani L, Contreras RG, Roldan ML, Moreno J, Lazaro A, Balda MS, Matter K, Cereijido M (2004). The polarized expression of NA+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells.

    2003

    • Matter K, Balda MS (2003). Signalling to and from tight junctions. Nature Reviews Molecular Cell Biology, 4(3), 225 - 236. doi:10.1038/nrm1055
    • Balda MS, Garrett MD, Matter K (2003). The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. The Journal of Cell Biology, 160(3), 423 - 432. doi:10.1083/jcb.200210020
    • Balda MS, Greenwood J, Adamson P, Matter K (2003). Differentiation of retinal pigment epithelium: The role of the tight junction associated transcription factor ZONAB.
    • Matter K, Balda MS (2003). Holey barrier: claudins and the regulation of brain endothelial permeability. The Journal of Cell Biology, 161(3), 459 - 460.
    • Balda MS, Matter K (2003). Epithelial cell adhesion and the regulation of gene expression. Trends in Cell Biology, 13(6), 310 - 318. doi:10.1016/S0962-8924(03)00105-3
    • Matter K, Balda MS (2003). Functional analysis of tight junctions. Methods, 30(3), 228 - 234.
    • Benais-Pont G, Punn A, Flores-Maldonado C, Eckert J, Raposo G, Fleming TP, Cereijido M, Balda MS, Matter K (2003). Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability. The Journal of Cell Biology, 160(5), 729 - 740. doi:10.1083/jcb.200211047

    2001

    • Pont-Benais G, Matter K, Balda MS (2001). Intracellular signalling in classical and new tight junction functions. In Cereijido M, Anderson JM (Ed.), Tight junctions (pp. 367 - 394). : CRC Press.
    • Matter K, Balda MS (2001). Tight junctions and the differentiation of polarized epithelia.

    2000

    • Balda MS, Matter K (2000). Transmembrane proteins of tight junctions.. Semin Cell Dev Biol, 11(4), 281 - 289. doi:10.1006/scdb.2000.0177
    • Balda MS, Matter K (2000). The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression.. EMBO J, 19(9), 2024 - 2033. doi:10.1093/emboj/19.9.2024
    • Balda MS, Flores-Maldonado C, Cereijido M, Matter K (2000). Multiple domains of occludin are involved in the regulation of paracellular permeability.. J Cell Biochem, 78(1), 85 - 96.
    • Huber D, Balda MS, Matter K (2000). Occludin modulates transepithelial migration of neutrophils.. J Biol Chem, 275(8), 5773 - 5778.

    1999

    • Balda MS, Matter K (1999). The tight junction protein ZO-1 and an associated transcription factor regulate the expression of an oncogene and cell cycle progression.
    • Matter K, Flores C, Cereijido M, Balda MS (1999). Multiple domains of occludin are involved in the regulation of tight junction functions.
    • Matter K, Balda MS (1999). Occludin and the functions of tight junctions.. Int Rev Cytol, 186, 117 - 146.

    1998

    • Huber D, Balda MS, Matter K (1998). Transepithelial migration of neutrophils.. Invasion Metastasis, 18(2), 70 - 80.
    • Matter K, Balda MS (1998). Biogenesis of tight junctions: the C-terminal domain of occludin mediates basolateral targeting.. J Cell Sci, 111 ( Pt 4), 511 - 519.
    • Balda MS, Matter K (1998). Commentary - Tight junctions. J CELL SCI, 111, 541 - 547.
    • Gut A, Kappeler F, Hyka N, Balda MS, Hauri HP, Matter K (1998). Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins.. EMBO J, 17(7), 1919 - 1929. doi:10.1093/emboj/17.7.1919
    • Gut A, Balda MS, Matter K (1998). The cytoplasmic domains of a beta1 integrin mediate polarization in Madin-Darby canine kidney cells by selective basolateral stabilization.. J Biol Chem, 273(45), 29381 - 29388.

    1997

    • Blum MS, Toninelli E, Anderson JM, Balda MS, Zhou J, O'Donnell L, Pardi R, Bender JR (1997). Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines.. Am J Physiol, 273(1 Pt 2), H286 - H294.

    1996

    • Balda MS, Anderson JM, Matter K (1996). The SH3 domain of the tight junction protein ZO-1 binds to a serine protein kinase that phosphorylates a region C-terminal to this domain.. FEBS Lett, 399(3), 326 - 332.
    • Balda MS, Whitney JA, Flores C, González S, Cereijido M, Matter K (1996). Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.. J Cell Biol, 134(4), 1031 - 1049.

    1995

    • Fallon MB, Brecher AR, Balda MS, Matter K, Anderson JM (1995). Altered hepatic localization and expression of occludin after common bile duct ligation.. Am J Physiol, 269(4 Pt 1), C1057 - C1062.
    • FALLON MB, BRECHER AR, BALDA MS, MATTER K, ANDERSON JM (1995). ALTERED HEPATIC LOCALIZATION AND EXPRESSION OF OCCLUDIN AFTER COMMON BILE-DUCT LIGATION. AM J PHYSIOL-CELL PH, 38(4), C1057 - C1062.
    • Van Itallie CM, Balda MS, Anderson JM (1995). Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells.. J Cell Sci, 108 ( Pt 4), 1735 - 1742.
    • BRECHER A, FALLON MB, BALDA MS, MATTER K, ANDERSON JM (1995). ALTERED EXPRESSION AND LOCALIZATION OF THE PUTATIVE TIGHT JUNCTION SEALING PROTEIN, OCCLUDIN, AFTER COMMON BILE-DUCT LIGATION.

    1994

    • BLUM MS, BALDA MS, ANDERSON JM, BENDER JR (1994). ACTIN CYTOSKELETAL REGULATION OF HUMAN ENDOTHELIAL-CELL TIGHT JUNCTION INTEGRITY.

    1993

    • Cereijido M, Ruiz O, Gonzalez- ML, Contrears RG, Balda MS, Garcia-Villegas MR (1993). The paracellular pathway: a small version of the kidney nephron. In Kenneth LA, Raub TJ (Ed.), Biological Barriers to Protein Delivery (pp. 3 - 21). : Plenum Press.
    • Anderson JM, Balda MS, Fanning AS (1993). The structure and regulation of tight junctions.. Curr Opin Cell Biol, 5(5), 772 - 778.
    • Willott E, Balda MS, Fanning AS, Jameson B, Van Itallie C, Anderson JM (1993). The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.. Proc Natl Acad Sci U S A, 90(16), 7834 - 7838.
    • CEREIJIDO M, BALDA MS, GONZALEZMARISCAL L, CONTRERAS RG, GALLARDO JM, GARCIAVILLEGAS MD (1993). THE MAKING OF A TIGHT JUNCTION. J CELL BIOCHEM, , 266 - 266.
    • Balda MS, Gonzalez-Mariscal L, Matter K, Cereijido M, Anderson JM (1993). Assembly of the tight junction: the role of diacylglycerol.. J Cell Biol, 123(2), 293 - 302.
    • WILLOTT E, BALDA MS, FANNING AS, JAMESON B, VANITALLIE C, ANDERSON JM (1993). THE HUMAN HEPATOCYTE TIGHT JUNCTION PROTEIN ZO-1 IS HOMOLOGOUS TO THE DROSOPHILA-DISKS-LARGE TUMOR-SUPPRESSOR.
    • Balda MS, Anderson JM (1993). Two classes of tight junctions are revealed by ZO-1 isoforms.. Am J Physiol, 264(4 Pt 1), C918 - C924.

    1992

    • KOPS SK, WEST AB, BALDA MS, TERWILLGER G, LOWE DK (1992). TRANSLOCATION DIFFERENCES OF VIRULENT AND AVIRULENT SALMONELLA-TYPHI STRAINS ACROSS CACO2 CELL MONOLAYERS.
    • Willott E, Balda MS, Heintzelman M, Jameson B, Anderson JM (1992). Localization and differential expression of two isoforms of the tight junction protein ZO-1.. Am J Physiol, 262(5 Pt 1), C1119 - C1124.
    • BALDA MS, ANDERSON JM (1992). ZO-1 ISOFORM DISTRIBUTION REVEALS 2 CLASSES OF TIGHT JUNCTIONS.
    • Balda MS, Fallon MB, Van Itallie CM, Anderson JM (1992). Structure, regulation, and pathophysiology of tight junctions in the gastrointestinal tract.. Yale J Biol Med, 65(6), 725 - 735.

    1991

    • Balda MS (1991). Intracellular signals in the assembly and sealing of tight junctions. In Cereijido M (Ed.), The Tight Junctions (pp. 121 - 137). : CRC Press, Boca Raton, Florida.
    • Balda MS, González-Mariscal L, Contreras RG, Macias-Silva M, Torres-Marquez ME, García-Sáinz JA, Cereijido M (1991). Assembly and sealing of tight junctions: possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin.. J Membr Biol, 122(3), 193 - 202.

    1989

    • Cereijido M, Balda MS, Ponce A, Bolivar JJ (1989). Molecular and physiological properties of plasma membranes: The role of ion channels. In (Ed.), Cell Function and Diseases (pp. 93 - 122). : Plenum Press.
    • Pirola CJ, Alvarez AL, Balda MS, Finkielman S, Nahmod VE (1989). Evidence for cholinergic innervation in dog renal tissue.. Am J Physiol, 257(5 Pt 2), F746 - F754.

    1988

    • Dabsys SM, Balda MS, Pirola CJ, Finkielman S, Nahmod VE (1988). Angiotensin converting enzyme activity in the amygdaloid complex in a neurogenic hypertensive model.. Clin Exp Hypertens A, 10(4), 605 - 615.

    1987

    • Pirola CJ, Scheucher A, Balda MS, Dabsys SM, Finkielman S, Nahmod VE (1987). Serotonin mediates cardiovascular responses to acetylcholine, bradykinin, angiotensin II and norepinephrine in the lateral septal area of the rat brain.. Neuropharmacology, 26(6), 561 - 566.
    • Scheucher A, Pirola CJ, Balda MS, Dabsys SM, Alvarez AL, Finkielman S, Nahmod VE (1987). Muscarinic M1 receptors in the lateral septal area mediate cardiovascular responses to cholinergic agonists and bradykinin: supersensitivity induced by chronic treatment with atropine.. Neuropharmacology, 26(2-3), 181 - 185.
    • DABSYS SM, BALDA MS, PIROLA CJ, VINDROLA O, GARCIA SI, FINKIELMAN S, NAHMOD VE (1987). THE DESTRUCTION OF VENTRAL NORADRENERGIC ACTIVITY PROVOKES HYPERTENSION AND AN INCREASE IN THE CONTENT OF ANGIOTENSIN-II AND META-ENCEPHALIN IN THE ANTERIOR HYPOTHALAMIC PREOPTIC AREA OF THE RAT.

    1986

    • Pirola CJ, Balda MS, Alvarez AL, Finkielman S, Nahmod VE (1986). Interaction between acetylcholine and bradykinin in the lateral septal area of the rat brain: involvement of muscarinic receptors in cardiovascular responses.. Neuropharmacology, 25(12), 1387 - 1393.
    • Balda MS, Pirola CJ, Dabsys SM, Finkielman S, Nahmod VE (1986). Saralasin blocks the effect of angiotensin II and extracellular fluid saline expansion on the Na-K-ATPase inhibitor release in rats.. Clin Exp Hypertens A, 8(6), 997 - 1008.
    • PIROLA CJ, SCHEUCHER A, BALDA MS, DABSYS SM, FINKIELMAN S, NAHMOD VE (1986). THE INTAKE ACTION OF ACETYLCHOLINE, NORADRENALIN, ANGIOTENSIN-II AND BRADYKININ INFUSED IN LATERAL SEPTAL AREA DEPENDS ON A SEROTONINERGIC WAY OF THE PREOPTICAL AREA OF THE ANTERIOR HYPOTHALAMUS.
    • DABSYS SM, BALDA MS, PIROLA CJ, SCHEUCHER A, FINKIELMAN S, NAHMOD VE (1986). ACTIVITY OF THE ANGIOTENSIN-I CONVERSION ENZYME IN CEREBRAL NUCLEI AND THE PINEAL-GLAND OF THE SPONTANEOUSLY HYPERTENSIVE RAT.

    1985

    • SCHEUCHER A, PIROLA CJ, BALDA MS, ALVAREZ SMDA, FINKIELMAN S, NAHMOD VE (1985). MUSCARINIC M1 RECEPTORS MEDIATE CARDIOVASCULAR-RESPONSES OF CHOLINERGIC AND BRADYKININ AGONISTS IN THE LATERAL SEPTAL AREA.

    1984

    • Pirola CJ, Balda MS, Finkielman S, Nahmod VE (1984). Increase in muscarinic receptors in rat intestine by thyrotropin releasing hormone (TRH).. Life Sci, 34(17), 1643 - 1649.
    • Nahmod VE, Balda MS, Pirola CJ, Cardinali DP (1984). Changes in plasma aldosterone levels and renin activity after bilateral superior cervical ganglionectomy in two strains of rats.. Acta Physiol Pharmacol Latinoam, 34(3), 263 - 269.

    1983

    • Pirola CJ, Balda MS, Finkielman S, Nahmod VE (1983). Thyrotropin-releasing hormone increases the number of muscarinic receptors in the lateral septal area of the rat brain.. Brain Res, 273(2), 387 - 391.
    • Benarroch EE, Balda MS, Finkielman S, Nahmod VE (1983). Neurogenic hypertension after depletion of norepinephrine in anterior hypothalamus induced by 6-hydroxydopamine administration into the ventral pons: role of serotonin.. Neuropharmacology, 22(1), 29 - 34.
    • BALDA MS, PIROLA CJ, FINKIELMAN S, NAHMOD VE (1983). INFUSED ANGIOTENSIN-II IN THE 3RD VENTRICLE OF THE RAT RELEASES AN INHIBITING FACTOR OF THE NA-K-ATPASE ENZYME.
    • PIROLA CJ, ALVAREZ AL, BALDA MS, FINKIELMAN S, NAHMOD VE (1983). THE INTRARENAL CHOLINERGIC SYSTEM THROUGH THE NATRIURETIC ACTION OF BRADYKININ - EFFECT OF DENERVATION.
    • PIROLA CJ, BALDA MS, FINKIELMAN S, NAHMOD VE (1983). THE LIBERATING HORMONE OF TYROTROPHINE INCREASES THE NUMBER OF MUSCARINIC RECEPTORS IN THE RAT INTESTINE.
    • PIROLA CJ, ALVAREZ A, BALDA MS, NAHMOD VE, FINKIELMAN S (1983). BRADYKININ INCREASES THE UPTAKE OF CHOLINES IN THE SEPTAL-LATERAL AREA OF THE RAT.
    • GENE R, JOLLY E, BALDA MS, PIROLA CJ, NAHMOD VE (1983). CORRELATION BETWEEN SARCOIDOTIC PULMONARY ACTIVITY AND PLASMA-LEVELS OF ANGIOTENSIN-I CONVERSION ENZYME.
    • Balda MS (1983). [Use of angiotensin II in the treatment of cancer].. Medicina (B Aires), 43(3), 350 - 352.
    • BALDA MS, PIROLA CJ, DABSYS SM, FINIELMAN S, NAHMOD VE (1983). MODIFICATION OF THE ACTIVITY OF THE CONVERSION ENZYME FOR ANGIOTENSIN-1 (KININASE-II) DURING RAT DEVELOPMENT - THE EFFECT OF 6-HYDROXIDOPAMINE ON THE HYPOTHALMUS, PINEAL-GLAND, ADRENAL-GLAND AND THE PITUITARY-GLAND. ACTA PHYSIOL LAT AM, 33(2), 184 - 185.

    1982

    • BALDA MS, PIROLA CJ, DABSYS SM, FINKIELMAN S, NAHMOD VE (1982). MODIFICATION OF THE ACTIVITY OF THE ANGIOTENSIN-I CONVERSION ENZYME DURING DEVELOPMENT OF THE RAT - EFFECT OF 6-HYDROXYDOPAMINE IN THE HYPOTHALAMUS, THE PINEAL-GLAND, THE ADRENAL-GLAND AND THE HYPOPHYSIS.
    • BENARROCH EE, PIROLA CJ, BALDA MS, FINKIELMAN S, NAHMOD VE (1982). A MODEL FOR NEUROGENIC HYPERTENSION - BILATERAL DESTRUCTION OF THE NORADRENERGIC VENTRAL BUNDLE.
    • Nahmod VE, Balda MS, Pirola CJ, Finkielman S, Gejman PV, Cardinali DP (1982). Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme.. Brain Res, 236(1), 216 - 220.
    • PIROLA CJ, ALVAREZ AL, BALDA MS, FINKIELMAN S, NAHMOD VE (1982). CHARACTERIZATION OF A PEPTIDE WITH IMMUNOREACTIVITY AND SIMILAR BIOLOGICAL EFFECT TO ANGIOTENSIN-I IN THE BRAIN OF THE DOG.
    • PIROLA CJ, BALDA MS, FINKIELMAN S, NAHMOD VE (1982). TRH INCREASES THE NUMBER OF MUSCARINIC RECEPTORS IN THE LATERAL SEPTAL AREA OF THE RAT DIENCEPHALON.
    • BENARROCH EE, BALDA MS, PIROLA CJ, FINKIELMAN S, NAHMOD VE (1982). NEUROGENIC HYPERTENSION THROUGH DEPLETION OF NORADRENALIN IN THE ANTERIOR HYPOTHALAMUS - INVOLUCRATE RECEPTORS AND PLASMATIC RENIN.

    1981

    • NAHMOD VE, BENARROCH EE, PIROLA CJ, ALVAREZ A, BALDA MS, CALBOSA HA, FINKIELMAN S (1981). EFFECT OF SQ-14225 ON PLASMA-RENIN ACTIVITY OF ESSENTIAL HYPERTENSIVE PATIENTS DURING EXERCISE.
    • BALDA MS, PIROLA CJ, GEJMAN PV, DABSYS SM, FINKIELMAN S, CARDINALLI DP, NAHMOD VE (1981). CIRCADIAN-RHYTHM AND SYMPATHETIC CONTROL OF THE CONVERSION ENZYME OF ANGIOTENSIN-I IN THE PINEAL-GLAND OF THE RAT.

    1980

    • NAHMOD VE, BENARROCH EE, PIROLA CJ, ALVAREZ A, BALDA MS, CALBOSA HA, FINKIELMAN S (1980). REVERSAL OF EFFECT OF EXERCISE ON PLASMA-RENIN ACTIVITY OF HYPERTENSIVES TREATED WITH SQ14225.
    • PIROLA CJ, BALDA MS, ALVAREZ AL, FINKIELMAN S, NAHMOD VE (1980). INHIBITORY EFFECT OF CAPTOPRIL ON RENAL RENIN SECRETION INDUCED BY RESTRICTIVE STRESS IN RATS.
    • BALDA MS, PIROLA CJ, DABSYS SM, ALVAREZ A, GEJMAN PV, FINKIELMAN S, NAHMOD VE (1980). EFFECT OF MATURATION ON LEVEL OF ANGIOTENSIN-1 CONVERTING ENZYME IN RAT PINEAL-GLAND.
    • BENARROCH EE, PIROLA CJ, ALVAREZ A, BALDA MS, FINKIELMAN S, NAHMOD VE (1980). CENTRAL ALPHA-ADRENERGIC MECHANISMS INHIBIT PRESSOR EFFECT OF BRADYKININ AND ACETYLCHOLINE IN LATERAL SEPTAL AREA.
    • NAHMOD VE, LASCANO EF, PIROLA CJ, BALDA MS, ALVAREZ A, GEJMAN PV, CARDINALI DP (1980). INHIBITORY EFFECT OF SYMPATHETIC NERVOUS-SYSTEM ON ACTIVITY OF RENIN-ANGIOTENSIN SYSTEM IN RAT PINEAL-GLAND.
    • PIROLA CJ, ALVAREZ A, BALDA MS, BENARROCH EE, FINKIELMAN S, NAHMOD VE (1980). BRADYKININ-MUSCARINE CHOLINERGIC RECEPTOR INTERACTION IN SEPTAL AREA OF RAT-BRAIN.

    1979

    • BENARROCH EE, PIROLA CJ, ALVAREZ A, BALDA MS, NAHMOD VE (1979). ANGIOTENSIN-II ACTIVITY IN HYPOTHALAMIC PREOPTIC REGION DURING DEPLETION OF SEROTONIN WITH 5,7-DIHYDROXYTRYPTAMINE.

    • Tsapara A, Luthert P, Greenwood J, Hill CS, Matter K, Balda MS (). The Rho activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration..